Search on: PIAS3 PROTEIN INHIBITOR OF ACTIVATED STAT 
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Descriptor English:   Protein Inhibitors of Activated STAT 
Descriptor Spanish:   Proteínas Inhibidoras de STAT Activados 
Descriptor Portuguese:   Proteínas Inibidoras de STAT Ativados 
Synonyms English:   PIAS Proteins
PIAS1 Protein
PIAS2 Protein Inhibitor of Activated STAT
PIAS3 Protein Inhibitor of Activated STAT
PIAS4 Protein Inhibitor of Activated STAT
PIAS1 Protein Inhibitor of Activated STAT  
Tree Number:   D12.644.360.024.319
D12.776.157.057.124
D12.776.476.024.402
Definition English:   A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription. 
History Note English:   2006(1998) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50781 
Unique Identifier:   D050828 

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